Cambios en la atención, el aprendizaje y la memoria durante las fluctuaciones de estradiol en estudiantes universitarias / Changes in the Attention, Learning and Memory during the Fluctuations of Estradiol in University Students

  • M.Isabel Gómez-León Universidad Internacional de La Rioja
Palabras clave: Atención, aprendizaje, memoria, estudiantes universitarias, estradiol

Resumen

ABSTRACT

With this investigation one tries to analyze the influence of the fluctuations of estradiol in the learning process of university students. The hormonal levels of 17- . estradiol have measured up in saliva, across kits ELISA (Enzyme-Linked ImmunoSorbent Assay) in 64 women, aged 18-19 years. The subjects realized the tests of memory and control atencional of Luria's battery DNA when his levels of estradiol were high and when these were lower. The studied women obtained significantly top punctuations in the curve of learning and in the tests of immediate memory and attention when they were during the more high beak of estradiol, that when the levels of estradiol were low.

RESUMEN

Con esta investigación se pretende analizar la influencia de las fluctuaciones de estradiol en el proceso de aprendizaje de estudiantes universitarias. Se han medido los niveles hormonales de 17- β estradiol en saliva, a través de kits ELISA (Enzyme-Linked ImmunoSorbent Assay) en 64 mujeres, de entre 18 y 19 años. Los sujetos realizaron las pruebas de memoria y control atencional de la batería de Luria DNA cuando sus niveles de estradiol eran más altos y cuando estos eran más bajos. Las mujeres estudiadas obtuvieron puntuaciones significativamente superiores en la curva de aprendizaje y en las pruebas de memoria inmediata y atención cuando se encontraban durante el pico más alto de estradiol, que cuando los niveles de estradiol eran bajos.

Biografía del autor/a

M.Isabel Gómez-León, Universidad Internacional de La Rioja
Docente en el departamento de psicobiología de la Universidad Internacional de la Rioja, Universidad Antonio de Nebrija y Universidad Camilo José Cela.

Citas

Ardila, A., Bernal, B. (2007). What can be localized in the brain? Toward a “factor” theory on brain organization of cognition. International Journal of Neuroscience,117:935- 969.

Arnoldo, T., Sánchez TJ. (2016). Luria's model of the functional units of the brain and the neuro-psychology of dreaming. Psychology in Russia, 9(4):80-93. http://dx.doi.org/10.11621/pir.2016.0407

Azcoitia, J.G., Yague, Garcia-Segura, L.M. (2011). Estradiol synthesis within the human brain. Neuroscience, 191:139–147

https://doi.org/10.1016/j.neuroscience.2011.02.012

Banciu, A., Banciu, D.D., Mustaciosu,C.C., Radu M., Cretoiu D., Xiao J., Cretoiu S.M., Suciu N., Radu B.M. (2018). Beta-Estradiol Regulates Voltage-Gated Calcium Channels and Estrogen Receptors in Telocytes from Human Myometrium. Int. J. Mol., 19(5), 1413

https://doi.org/10.3390/ijms19051413

Barth, C., Steele, C., Mueller, K., Rekkas, V., Arélin, K., Pampel, A., Burmann, I., Kratzsch, J., Villringer, A., Sacher, J. (2016). In-vivo Dynamics of the Human Hippocampus across the Menstrual Cy-cle. Scientific Reports, 6:32833.

https://doi.org/10.1038/srep32833

Bausela, E. (2010). Curva de aprendizaje de Luria en personas con daño cerebral. Enseñanza e Investigación en Psicología,15(1):147-158

Castejón, J.L., Gilar, R., Miñano, P.,Veas , A. (2016). Identificación y establecimiento de las caracterís-ticas motivacionales y actitudinales de los estudiantes con rendimiento académico menor de lo esperado según su capacidad (underachievement). European Journal of Education and Psychology, 9(2), 63-71 https://doi.org/10.1016/j.ejeps.2016.04.001

de Lacalle S., Hyler B., Borowski T. (2008) Estrogen, Cholinergic System and Cognition. In: Ritsner M.S., Weizman A. (eds) Neuroactive Steroids in Brain Function, Behavior and Neuropsychia-tric Disorders. Springer, Dordrecht https://doi.org/10.1007/978-1-4020-6854-6_6

Del Valle, M. V., y Urquijo, S. (2015). Relaciones de las estrategias de codificación mnésica y la capacidad de aprendizaje con el desempeño académico de estudiantes universitarios. Psico-logía Educativa, 21(1), 27-37.

https://doi.org/10.1016/j.pse.2015.02.004

Diaz, R. (2009). Estrogen-induced plasticity from cells to circuits: predictions for cognitive function. Trends in Pharmacological Sciences. 30(4):212-222

https://doi.org/10.1016/j.tips.2008.12.006

Dreher, J.C., Schmidt, P.J., Kohn, P., Furman, D., Rubinow, D., Berman, K. (2007). Menstrual cycle phase modulates reward-related neural function in women.PNAS, 104 (7):2465-2470

https://doi.org/10.1073/pnas.0605569104

Dumontheil, I. (2015). Development of the social brain during adolescence. Psicología Educativa 21(2): 117-24

https://doi.org/10.1016/j.pse.2015.08.001

Fernández-Zabala, A., Goñi, E., Camino, I., and Zulaika, L. M. (2016). Family and school context in school engagement. European Journal of Education and Psychology, 9(2), 47-5

https://doi.org/10.30552/ejep.v9i2.136

Girard, R., Météreau, E., Thomas, J., Pugeat, M., Qu, C., Dreher, J.C. (2017). Hormone therapy at early post-menopause increases cognitive control-related prefrontal activity. Sci Rep., 7:44917

http://dx.doi.org/10.1038/srep44917

Hajszan, T., Hoyk Z., Garcia-Segura L.M., Parducz A. (2008) Effects of Estradiol and DHEA on Morpho-logical Synaptic Plasticity. In: Ritsner M.S., Weizman A. (eds) Neuroactive Steroids in Brain Function, Behavior and Neuropsychiatric Disorders. Springer, Dordrecht.

https://doi.org/10.1007/978-1-4020-6854-6_8

Hwang, D.S., Kim, N., Choi, J.G., Kim, H.G., Kim, H., Oh, M.S. (2017). Dangguijakyak-san ameliorates memory deficits in ovariectomized mice by upregulating hippocampal estrogen synthesis. BMC Complement Altern Med. Nov 25;17(1):501.

https://doi.org/10.1186/s12906-017-015-6.

Jódar-Vicente, M. (2004). Funciones cognitivas del lóbulo frontal. Rev Neurol, 39 (02):178-182

Luine, V. (2016) Estradiol: Mediator of memories, spine density and cognitive resilience to stress in female rodents Journal of Steroid Biochemistry and Molecular Biology, 160: 189-195

https://doi.org/10.1016/j.jsbmb.2015.07.022

Luine, V. (2014) Estradiol and cognitive function: Past, present and future. Hormones and Behavior, 66(4):602-6018.

https://doi.org/10.1016/j.yhbeh.2014.08.011

Luria, A.R. (1980). Higher Cortical Functions in Man. (2º Ed.). New York: Basic Books.

Mahmoud, R., Wainwright, S.R., Galea, L.A. (2016). Sex hormones and adult hippocampal neurogene-sis: Regulation, implications, and potential mechanisms. Front Neuroendocrinol 40:129–152.

Maki, P., Resnick, S. (2001). Effects of estrogen on patterns of brain activity at rest and during cognitive activity: a review of neuroimaging studies. Neuroimage, 14(4):789-801

https://doi.org/10.1006/nimg.2001.0887

Manga, D., Ramos, F. (2000). Luria DNA: Diagnóstico Neuropsicológico de Adultos. Madrid: TEA

Navea-Martín A., Suárez-Riveiro J.M. (2016). Estudio sobre la utilización de estrategias de automoti-vación en estudiantes universitarios. Psicología Educativa 23 (2) 115-21

https://doi.org/10.1016/j.pse.2016.08.001

Nishimura, K., Doi, D., Samata, B., Murayama, S., Tahara, T., Onoe, H., Takahashi, J. (2016). Estradiol Facilitates Functional Integration of iPSC -Derived Dopaminergic Neurons into Striatal Neu-ronal Circuits via Activation of Integrin alpha5beta1. Stem Cell Reports., 6(4): 511 -24.

https://doi.org/10.1016/j.stemcr.2016.02.008

Pachalska, M., Kaczmarck, B.L.J. (2012). Alexander Romanovich Luria (1902-1977) and the microge-netic approach to the diagnosis and rehabilitation of TBI patients. Acta Neuropsycholagi-ca,10:341-369.

https://doi.org/10.5604/17307503.1023670

Pletzer, B., Harris, T.A., Ortner, T. (2017). Sex and menstrual cycle influences on three aspects of attention, Physiology & behavior, Oct 1;179:384-390.

https://doi.org/10.1016/j.physbeh.2017.07.012

Pletzer, B., Kronbichler, M., Aichhorn, M., Bergmann, J., Ladurner, G., Kerschbaum, H.H. (2010). Menstrual cycle and hormonal contraceptive use modulate human brain structure. Brain Res., 1348 :55-62

https://doi.org/10.1016/j.brainres.2010.06.019

Protopopescu, X., Pan, H., Root, J., Altemus, M., Polanecsky, M., McEwen, B., Silbersweig, D., Stern, E. (2008). Hippocampal structural changes across the menstrual cycle. Hippocampus, 18, 985–988

https://doi.org/10.1002/hipo.20468

Protopopescu, X., Butler, T., Pan, H., Root, J., Altemus, M., Polanecsky, M. et al. (2008). Hippocampal structural changes across the menstrual cycle. Hippocampus,18(10):985-8

https://doi.org/10.1002/hipo.20468

Resnick, SM., Maki, P.M., Golski, S., Kraut, M.A., Zonderman, A.B. (2017). Effects of estrogen replace-ment therapy on PET cerebral blood flow and neuropsychological performance. Horm Behav, 34: 171-182

https://doi.org/10.1006/hbeh.1998.1476

Rueda-Revé, L., Contador, I., Fernández-Calvo B., Ramos F., Manga D., Villarejo A. (2017). Utilidad de la batería Luria diagnóstico neuropsicológico de adultos. Papeles del Psicólogo, 38(3), pp. 195-203

https://doi.org/10.23923/pap.psicol2017.2842

Sánchez, J.C., López-Zapata, D.F., Pinzón, O.A. (2014). Effects of 17beta-estradiol and IGF-1 on L-type voltage-activated and stretch-activated calcium currents in cultured rat cortical neurons. Neuro Endocrinol Lett, 35(8):724-32.

https://doi.org/10.23923/pap.psicol2017.2842

Sattari, N., McDevitt, E.A., Panas, D., Niknazar, M., Ahmadi, M., Naji, M., Baker, FC., Mednick, S.C. (2017). The effect of sex and menstrual phase on memory formation during a nap. Neurobio-logy of learning and memory, Nov;145:119-128.

https://doi.org/10.1016/j.nlm.2017.09.007

Sellers, K., Raval, P., Srivastava, D.P. (2015). Molecular signature of rapid estrogen regulation of synaptic connectivity and cognition. Front. Neuroendocrinol, 36C:72–89

https://doi.org/10.1016/j.yfrne.2014.08.001

Sellers, K.J., Erli, F., Raval, P., Watson, I.A., Chen, D., Srivastava, D.P. (2015). Rapid modulation of synaptogenesis and spinogenesis by 17beta -estradiol in primary cortical neurons. Front Cell Neurosci, 9:137

https://doi.org/10.3389/fncel.2015.00137

Smith, C. T., Sierra, Y., Oppler, S. H., and Boettiger, C. A. (2014). Ovarian cycle effects on immediate reward selection bias in humans: a role for estradiol. J. Neurosci. 34, 5468–5476.

https://doi.org/10.1523/JNEUROSCI.0014-14.2014

Soma, M., Kim, J., Kato, A., Kawato, S. (2018). Src Kinase Dependent Rapid Non-genomic Modulation of Hippocampal Spinogenesis Induced by Androgen and Estrogen. Frontiers in Neuroscience. 12,282

https://doi.org/10.3389/fnins.2018.00282

Srivastava, D.P., Woolfrey, K.M., Penzes P. (2013). Rapid Modulation of Neuroplasticity by Brain Estrogen Pharmacological Reviews October 1, 65 (4) 1318-1350; https://doi.org/10.1124/pr.111.005272

Tirapu-Ustárroz, J., Muñoz-Céspedes, J.M. (2005). Memoria y funciones ejecutivas. Rev Neurol, 41 (08):475-484

Wang, X., Wang, Y., Ma, L., Zhang, R., De, Y., Yang, X., … Wu, Q. (2015). Development of an improved competitive ELISA based on a monoclonal antibody against lipopolysaccharide for the detec-tion of bovine brucellosis. BMC Veterinary Research, 11, 118.

http://doi.org/10.1186/s12917-015-0436-3

Weber, M.T., Rubin, L.H., Maki, P.M. (2013). Cognition in perimenopause: The effect of transition stage. Menopause, 20(5):511-7

http://doi.org/10.1097/GME.0b013e31827655e5

Publicado
2019-10-22
Cómo citar
Gómez-León, M. (2019). Cambios en la atención, el aprendizaje y la memoria durante las fluctuaciones de estradiol en estudiantes universitarias / Changes in the Attention, Learning and Memory during the Fluctuations of Estradiol in University Students. Revista Internacional De Educación Y Aprendizaje, 7(3), pp. 129-138. Recuperado a partir de https://journals.epistemopolis.org/educacion/article/view/2019
Sección
Artículos